Only two factors determine a bullets external ballistics. BC and velocity. Two bullets that have the same shape and ratio of length to width will have the same BC regardless of their relative weights. At 200 yds or less a bullets BC will not come into play as much. The high BC bullets will shed velocity slower than low BC bullets. At 500 or 600 yds this will make a big difference, but you are not interested in shooting steel at 500 yds. You have to understand that the 300 Whisper was designed to shoot bad guys out to 300 meters. Deer will react different. Match Kings will let you down. The theory of MKs is that they will turn (tumble) in the deer and cut a wound that looks like a knife went through it. Mks don't always do this. My experience is a 50/50 chance. When they work it is spectacular, but you will loose deer. The larger caliber bullets do more damage and do not rely on the bullet turning. I will include a pic of a 300 Whisper kill and a 458 SOCOM. Both are expanding. I suggest you get a ballistic program and play with it some. Get onto youtube and listen to Whispers and .44s SOCOM and whatever. In the end I am some guy you never met, but I have been there and done that.
http://lmgtfy.com/?q=youtube+suppressed+rifle
This is a thread on the .44 mag. Will a 240 .44 bullet kill a deer? Nope you have to use a 300 gr
http://www.silencertalk.com/forum/viewtopic.php?t=41897