Smith & Wesson's 300 is only different in that it's chambered in 300 Whisper, a wildcat cartridge that the 300 BLK is remarkably similar to; it is only shorter in overall length, which means that 300 BLK can be safely and accurately fired in a gun chambered in 300 Whisper, which is ballistically identical but a little more expensive
It is safer to fire Whisper(R) in a BLK chamber than BLK in a Whisper chamber - depending on which Whisper chamber it is. There are at least two and maybe four.