Trajectory the 6mm BC's are better.
Energy the 25 is better.
You need to define ballistics more.
I voted 243WSSM and here is why:
Under 300 yards
Deer and Smaller Game
The ammo selection for the 25WSSM is very limited because of C.O.A.L.
Even the 243WSSM can't feed all of the low drag bullets.
I have never heard of feeding issues with mine or any other WSSM AR if you keep the COAL down to fit in the magazine. Saying the 243WSSM doesn't feed as reliable as the 25WSSM, where did you hear this? Mines never had a hick-up.
You need to talk to the guy who pioneered the WSSM platform in the AR, Mike Milli of Dedicated Technology. He developed the platform with the aid of Olympic Arms and still builds these rifles.
He deer hunts with the 25WSSM but will explain it's short-comings. The majority of predator hunters that use the AR in a WSSM platform chose the 243WSSM. It is also very adequate for deer size and smaller game.
He is currently also making 6.5WSSM, 7mmWSSM, 300WSSM, 338WSSM and 358WSSM
Here is Mike's contact info:
Monday - Friday 8:30 AM to 4:30 PM Central
Office/shop line: (218) 444-7419
You might also look on his website:
http://www.dtechsuperstore.com/WSSM%20page.htm
Here in another place that has tons of users of his guns and many using the WSSM platform: (click on forums in top right)
http://www.predatormastersforums.com