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A question you didn't answer is what gun are you shooting this in???
If you have a 98 Mauser action or maybe a remington 700 than you might be fine with the experiment but if you're shooting this in an AR I'd be hesitant to even think about fiddling with this. I know the AR isn't a sissy cheap weak toy but when they go its usually much closer to the shooters face. Over pressure in the gas system can cause problems for the shooter too doing things like blowing out magwells etc.
Also consider that the rifle you have may be set up to fire the 123gr standard projo's so what rifling twist do you have? Will your 200 gr slugs stabilize?
Second thing here is like others said....don't compare cartridges for bullet weight, pressure and load. They don't compare and using that info will just make you mad.
Last thing, try something other than H110. As more and more people shoot this powder in oddball rounds like the whisper we keep seeing strange things happen. Temperature sensitivity and load density issues make it a bad powder to experiment with in this way. Look to some of the more consistant types like N110, 2400, H4227 etc. As Richard noted the Quickload program is a good way to get some idea of starting point.
Good luck
Frank
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