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Just keep in mind that Trailboss is a pretty fast powder, and as such, the difference of a couple grains could be a safe load or could blow primers. Work up in small increments and watch for all the usual signs. With a lighter bullet, I'd say you could probably get close to 100% case fill, but that may not be the case with a 220. Make sure you aren't compressing it any.
-Dan
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