As Fritzcat eluded to, Trailboss is probably an ideal powder for the .300 Whisper. It's great for using in large volume cases where you would typically only use a small amount of powder.
It is sometimes difficult to load subsonic .308 and similar rifle cartridges because you have so much room left in the case after charging with powder. This can make it difficult to get consistent results. One solution to this was to make reduced capacity cases, where the outside dimensions of the case were the same, but the case walls are very thick, only leaving a small amount of room for powder. Trailboss makes it easier to fill the case without overcharging it.
The .300 Whisper was designed to efficiently push a heavy bullet with minimal extra room in the case. There is no need to use a bulky powder like Trailboss. As noted, you probably can't get enough Trailboss in the case to push the bullet anywhere near 1000 fps.
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